{"comeds":[{"co_drug":"dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate","co_occurrences":5},{"co_drug":"gabapentin","co_occurrences":4},{"co_drug":"alprazolam","co_occurrences":4},{"co_drug":"melatonin","co_occurrences":4},{"co_drug":"escitalopram","co_occurrences":4},{"co_drug":"methylphenidate hydrochloride","co_occurrences":3},{"co_drug":"sertraline hydrochloride","co_occurrences":3},{"co_drug":"levothyroxine sodium","co_occurrences":3},{"co_drug":"aspirin","co_occurrences":2},{"co_drug":"gabapentin (gabapentin)","co_occurrences":2},{"co_drug":"clonidine","co_occurrences":2},{"co_drug":"docusate sodium","co_occurrences":2}],"kpis":{"death_reports":12,"pct_serious":"55.1","serious_reports":493,"total_reports":894},"reactions":[{"n":68,"reaction_term":"Drug ineffective"},{"n":59,"reaction_term":"Product substitution issue"},{"n":50,"reaction_term":"Product quality issue"},{"n":44,"reaction_term":"Prescribed overdose"},{"n":35,"reaction_term":"Fatigue"},{"n":31,"reaction_term":"Headache"},{"n":30,"reaction_term":"Disturbance in attention"},{"n":30,"reaction_term":"Drug effect decreased"},{"n":27,"reaction_term":"Feeling abnormal"},{"n":25,"reaction_term":"Insomnia"},{"n":22,"reaction_term":"Inappropriate schedule of drug administration"},{"n":18,"reaction_term":"Anxiety"},{"n":18,"reaction_term":"Decreased appetite"},{"n":17,"reaction_term":"Pain"},{"n":16,"reaction_term":"Off label use"}],"timeline":[{"n":11,"quarter":"Wed, 01 Jan 2014 00:00:00 GMT"},{"n":60,"quarter":"Tue, 01 Apr 2014 00:00:00 GMT"},{"n":60,"quarter":"Tue, 01 Jul 2014 00:00:00 GMT"},{"n":150,"quarter":"Wed, 01 Oct 2014 00:00:00 GMT"},{"n":19,"quarter":"Thu, 01 Jan 2015 00:00:00 GMT"},{"n":2,"quarter":"Wed, 01 Jul 2015 00:00:00 GMT"},{"n":1,"quarter":"Fri, 01 Jan 2016 00:00:00 GMT"},{"n":2,"quarter":"Sat, 01 Apr 2017 00:00:00 GMT"},{"n":1,"quarter":"Mon, 01 Oct 2018 00:00:00 GMT"}]}